AustralieFrV1, Main, Exploration, bibRecord, 002198

Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.

Identifieur interne : 002198 ( Main/Exploration ); précédent : 002197; suivant : 002199

Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.

Auteurs : Andrea Cipriani [Royaume-Uni] ; Xinyu Zhou [République populaire de Chine] ; Cinzia Del Giovane [Italie] ; Sarah E. Hetrick [Australie] ; Bin Qin [République populaire de Chine] ; Craig Whittington [États-Unis] ; David Coghill [Australie] ; Yuqing Zhang [République populaire de Chine] ; Philip Hazell [Australie] ; Stefan Leucht [Allemagne] ; Pim Cuijpers [Pays-Bas] ; Juncai Pu [République populaire de Chine] ; David Cohen [France] ; Arun V. Ravindran [Canada] ; Yiyun Liu [République populaire de Chine] ; Kurt D. Michael [États-Unis] ; Lining Yang [République populaire de Chine] ; Lanxiang Liu [République populaire de Chine] ; Peng Xie [Australie]

Source :

Lancet (London, England) [ 1474-547X ] ; 2016.

RBID : pubmed:27289172

Descripteurs français

English descriptors

KwdEn :
- Adolescent, Amitriptyline (administration & dosage), Amitriptyline (adverse effects), Antidepressive Agents (administration & dosage), Antidepressive Agents (adverse effects), Bayes Theorem, Child, Citalopram (administration & dosage), Citalopram (adverse effects), Clomipramine (administration & dosage), Clomipramine (adverse effects), Confounding Factors (Epidemiology), Depressive Disorder, Major (drug therapy), Desipramine (administration & dosage), Desipramine (adverse effects), Double-Blind Method, Drug Administration Schedule, Duloxetine Hydrochloride (administration & dosage), Duloxetine Hydrochloride (adverse effects), Evidence-Based Medicine, Fluoxetine (administration & dosage), Fluoxetine (adverse effects), Humans, Imipramine (administration & dosage), Imipramine (adverse effects), Mianserin (administration & dosage), Mianserin (adverse effects), Mianserin (analogs & derivatives), Nortriptyline (administration & dosage), Nortriptyline (adverse effects), Paroxetine (administration & dosage), Paroxetine (adverse effects), Randomized Controlled Trials as Topic, Research Design, Sertraline (administration & dosage), Sertraline (adverse effects), Treatment Outcome, Triazoles (administration & dosage), Triazoles (adverse effects), Venlafaxine Hydrochloride (administration & dosage), Venlafaxine Hydrochloride (adverse effects).
MESH :
- chemical , administration & dosage : Amitriptyline, Antidepressive Agents, Citalopram, Clomipramine, Desipramine, Duloxetine Hydrochloride, Fluoxetine, Imipramine, Mianserin, Nortriptyline, Paroxetine, Sertraline, Triazoles, Venlafaxine Hydrochloride.
- chemical , adverse effects : Amitriptyline, Antidepressive Agents, Citalopram, Clomipramine, Desipramine, Duloxetine Hydrochloride, Fluoxetine, Imipramine, Mianserin, Nortriptyline, Paroxetine, Sertraline, Triazoles, Venlafaxine Hydrochloride.
- chemical , analogs & derivatives : Mianserin.
- drug therapy : Depressive Disorder, Major.
- Adolescent, Bayes Theorem, Child, Confounding Factors (Epidemiology), Double-Blind Method, Drug Administration Schedule, Evidence-Based Medicine, Humans, Randomized Controlled Trials as Topic, Research Design, Treatment Outcome.

Abstract

Major depressive disorder is one of the most common mental disorders in children and adolescents. However, whether to use pharmacological interventions in this population and which drug should be preferred are still matters of controversy. Consequently, we aimed to compare and rank antidepressants and placebo for major depressive disorder in young people.

DOI: 10.1016/S0140-6736(16)30385-3
PubMed: 27289172

Affiliations:

Le document en format XML

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<author><name sortKey="Leucht, Stefan" sort="Leucht, Stefan" uniqKey="Leucht S" first="Stefan" last="Leucht">Stefan Leucht</name>
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<country xml:lang="fr">République populaire de Chine</country>
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<wicri:noRegion>Chongqing</wicri:noRegion>
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<author><name sortKey="Cohen, David" sort="Cohen, David" uniqKey="Cohen D" first="David" last="Cohen">David Cohen</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Child and Adolescent Psychiatry, Hôpital Pitié-Salpétrière, Institut des Systèmes Intelligents et Robotiques, Université Pierre et Marie Curie, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
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</placeName>
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</affiliation>
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<author><name sortKey="Ravindran, Arun V" sort="Ravindran, Arun V" uniqKey="Ravindran A" first="Arun V" last="Ravindran">Arun V. Ravindran</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON</wicri:regionArea>
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<author><name sortKey="Liu, Yiyun" sort="Liu, Yiyun" uniqKey="Liu Y" first="Yiyun" last="Liu">Yiyun Liu</name>
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<country xml:lang="fr">République populaire de Chine</country>
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<author><name sortKey="Michael, Kurt D" sort="Michael, Kurt D" uniqKey="Michael K" first="Kurt D" last="Michael">Kurt D. Michael</name>
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<author><name sortKey="Yang, Lining" sort="Yang, Lining" uniqKey="Yang L" first="Lining" last="Yang">Lining Yang</name>
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<country xml:lang="fr">République populaire de Chine</country>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing</wicri:regionArea>
<wicri:noRegion>Chongqing</wicri:noRegion>
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<author><name sortKey="Xie, Peng" sort="Xie, Peng" uniqKey="Xie P" first="Peng" last="Xie">Peng Xie</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. Electronic address: xiepeng973@126.com.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China; South Australian Health and Medical Research Institute, Adelaide, South Australia</wicri:regionArea>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.</title>
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<author><name sortKey="Zhou, Xinyu" sort="Zhou, Xinyu" uniqKey="Zhou X" first="Xinyu" last="Zhou">Xinyu Zhou</name>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing</wicri:regionArea>
<wicri:noRegion>Chongqing</wicri:noRegion>
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<author><name sortKey="Del Giovane, Cinzia" sort="Del Giovane, Cinzia" uniqKey="Del Giovane C" first="Cinzia" last="Del Giovane">Cinzia Del Giovane</name>
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<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Diagnostic, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Modena</wicri:regionArea>
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<author><name sortKey="Hetrick, Sarah E" sort="Hetrick, Sarah E" uniqKey="Hetrick S" first="Sarah E" last="Hetrick">Sarah E. Hetrick</name>
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<wicri:regionArea>Orygen, The National Centre of Excellence in Youth Mental Health, University of Melbourne, Melbourne, VIC</wicri:regionArea>
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</placeName>
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<author><name sortKey="Qin, Bin" sort="Qin, Bin" uniqKey="Qin B" first="Bin" last="Qin">Bin Qin</name>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing</wicri:regionArea>
<wicri:noRegion>Chongqing</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Whittington, Craig" sort="Whittington, Craig" uniqKey="Whittington C" first="Craig" last="Whittington">Craig Whittington</name>
<affiliation wicri:level="2"><nlm:affiliation>Doctor Evidence, Santa Monica, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Doctor Evidence, Santa Monica, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Coghill, David" sort="Coghill, David" uniqKey="Coghill D" first="David" last="Coghill">David Coghill</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Neuroscience, School of Medicine, University of Dundee, Dundee, UK; Department of Paediatrics, and Department of Psychiatry, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Division of Neuroscience, School of Medicine, University of Dundee, Dundee, UK; Department of Paediatrics, and Department of Psychiatry, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC</wicri:regionArea>
<wicri:noRegion>VIC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Yuqing" sort="Zhang, Yuqing" uniqKey="Zhang Y" first="Yuqing" last="Zhang">Yuqing Zhang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing</wicri:regionArea>
<wicri:noRegion>Chongqing</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hazell, Philip" sort="Hazell, Philip" uniqKey="Hazell P" first="Philip" last="Hazell">Philip Hazell</name>
<affiliation wicri:level="1"><nlm:affiliation>Discipline of Psychiatry, Sydney Medical School, Concord West, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Discipline of Psychiatry, Sydney Medical School, Concord West, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leucht, Stefan" sort="Leucht, Stefan" uniqKey="Leucht S" first="Stefan" last="Leucht">Stefan Leucht</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.</nlm:affiliation>
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<region type="district" nuts="2">District de Haute-Bavière</region>
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<orgName type="university">Université technique de Munich</orgName>
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</author>
<author><name sortKey="Cuijpers, Pim" sort="Cuijpers, Pim" uniqKey="Cuijpers P" first="Pim" last="Cuijpers">Pim Cuijpers</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Clinical, Neuro- and Developmental Psychology, VU University Amsterdam, Amsterdam, Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Clinical, Neuro- and Developmental Psychology, VU University Amsterdam, Amsterdam</wicri:regionArea>
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<region nuts="2" type="province">Hollande-Septentrionale</region>
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<author><name sortKey="Pu, Juncai" sort="Pu, Juncai" uniqKey="Pu J" first="Juncai" last="Pu">Juncai Pu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing</wicri:regionArea>
<wicri:noRegion>Chongqing</wicri:noRegion>
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<author><name sortKey="Cohen, David" sort="Cohen, David" uniqKey="Cohen D" first="David" last="Cohen">David Cohen</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Child and Adolescent Psychiatry, Hôpital Pitié-Salpétrière, Institut des Systèmes Intelligents et Robotiques, Université Pierre et Marie Curie, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Child and Adolescent Psychiatry, Hôpital Pitié-Salpétrière, Institut des Systèmes Intelligents et Robotiques, Université Pierre et Marie Curie, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
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<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
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<orgName type="university">Université Pierre-et-Marie-Curie</orgName>
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</author>
<author><name sortKey="Ravindran, Arun V" sort="Ravindran, Arun V" uniqKey="Ravindran A" first="Arun V" last="Ravindran">Arun V. Ravindran</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
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</author>
<author><name sortKey="Liu, Yiyun" sort="Liu, Yiyun" uniqKey="Liu Y" first="Yiyun" last="Liu">Yiyun Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing</wicri:regionArea>
<wicri:noRegion>Chongqing</wicri:noRegion>
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</author>
<author><name sortKey="Michael, Kurt D" sort="Michael, Kurt D" uniqKey="Michael K" first="Kurt D" last="Michael">Kurt D. Michael</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Psychology, Appalachian State University, Boone, NC, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychology, Appalachian State University, Boone, NC</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yang, Lining" sort="Yang, Lining" uniqKey="Yang L" first="Lining" last="Yang">Lining Yang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing</wicri:regionArea>
<wicri:noRegion>Chongqing</wicri:noRegion>
</affiliation>
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<author><name sortKey="Liu, Lanxiang" sort="Liu, Lanxiang" uniqKey="Liu L" first="Lanxiang" last="Liu">Lanxiang Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing</wicri:regionArea>
<wicri:noRegion>Chongqing</wicri:noRegion>
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<author><name sortKey="Xie, Peng" sort="Xie, Peng" uniqKey="Xie P" first="Peng" last="Xie">Peng Xie</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. Electronic address: xiepeng973@126.com.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China; South Australian Health and Medical Research Institute, Adelaide, South Australia</wicri:regionArea>
<wicri:noRegion>South Australia</wicri:noRegion>
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<series><title level="j">Lancet (London, England)</title>
<idno type="eISSN">1474-547X</idno>
<imprint><date when="2016" type="published">2016</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Amitriptyline (administration & dosage)</term>
<term>Amitriptyline (adverse effects)</term>
<term>Antidepressive Agents (administration & dosage)</term>
<term>Antidepressive Agents (adverse effects)</term>
<term>Bayes Theorem</term>
<term>Child</term>
<term>Citalopram (administration & dosage)</term>
<term>Citalopram (adverse effects)</term>
<term>Clomipramine (administration & dosage)</term>
<term>Clomipramine (adverse effects)</term>
<term>Confounding Factors (Epidemiology)</term>
<term>Depressive Disorder, Major (drug therapy)</term>
<term>Desipramine (administration & dosage)</term>
<term>Desipramine (adverse effects)</term>
<term>Double-Blind Method</term>
<term>Drug Administration Schedule</term>
<term>Duloxetine Hydrochloride (administration & dosage)</term>
<term>Duloxetine Hydrochloride (adverse effects)</term>
<term>Evidence-Based Medicine</term>
<term>Fluoxetine (administration & dosage)</term>
<term>Fluoxetine (adverse effects)</term>
<term>Humans</term>
<term>Imipramine (administration & dosage)</term>
<term>Imipramine (adverse effects)</term>
<term>Mianserin (administration & dosage)</term>
<term>Mianserin (adverse effects)</term>
<term>Mianserin (analogs & derivatives)</term>
<term>Nortriptyline (administration & dosage)</term>
<term>Nortriptyline (adverse effects)</term>
<term>Paroxetine (administration & dosage)</term>
<term>Paroxetine (adverse effects)</term>
<term>Randomized Controlled Trials as Topic</term>
<term>Research Design</term>
<term>Sertraline (administration & dosage)</term>
<term>Sertraline (adverse effects)</term>
<term>Treatment Outcome</term>
<term>Triazoles (administration & dosage)</term>
<term>Triazoles (adverse effects)</term>
<term>Venlafaxine Hydrochloride (administration & dosage)</term>
<term>Venlafaxine Hydrochloride (adverse effects)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Amitriptyline (administration et posologie)</term>
<term>Amitriptyline (effets indésirables)</term>
<term>Antidépresseurs (administration et posologie)</term>
<term>Antidépresseurs (effets indésirables)</term>
<term>Calendrier d'administration des médicaments</term>
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<term>Chlorhydrate de duloxétine (effets indésirables)</term>
<term>Chlorhydrate de venlafaxine (administration et posologie)</term>
<term>Chlorhydrate de venlafaxine (effets indésirables)</term>
<term>Citalopram (administration et posologie)</term>
<term>Citalopram (effets indésirables)</term>
<term>Clomipramine (administration et posologie)</term>
<term>Clomipramine (effets indésirables)</term>
<term>Désipramine (administration et posologie)</term>
<term>Désipramine (effets indésirables)</term>
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<term>Facteurs de confusion (épidémiologie)</term>
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<term>Fluoxétine (effets indésirables)</term>
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<term>Paroxétine (effets indésirables)</term>
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<term>Résultat thérapeutique</term>
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<term>Sertraline (effets indésirables)</term>
<term>Théorème de Bayes</term>
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<term>Triazoles (effets indésirables)</term>
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<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Amitriptyline</term>
<term>Antidepressive Agents</term>
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<term>Desipramine</term>
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<term>Fluoxetine</term>
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<term>Paroxetine</term>
<term>Sertraline</term>
<term>Triazoles</term>
<term>Venlafaxine Hydrochloride</term>
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<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Amitriptyline</term>
<term>Antidepressive Agents</term>
<term>Citalopram</term>
<term>Clomipramine</term>
<term>Desipramine</term>
<term>Duloxetine Hydrochloride</term>
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<term>Nortriptyline</term>
<term>Paroxetine</term>
<term>Sertraline</term>
<term>Triazoles</term>
<term>Venlafaxine Hydrochloride</term>
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<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Mianserin</term>
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<term>Chlorhydrate de duloxétine</term>
<term>Chlorhydrate de venlafaxine</term>
<term>Citalopram</term>
<term>Clomipramine</term>
<term>Désipramine</term>
<term>Fluoxétine</term>
<term>Imipramine</term>
<term>Miansérine</term>
<term>Nortriptyline</term>
<term>Paroxétine</term>
<term>Sertraline</term>
<term>Triazoles</term>
</keywords>
<keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>Miansérine</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Depressive Disorder, Major</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Amitriptyline</term>
<term>Antidépresseurs</term>
<term>Chlorhydrate de duloxétine</term>
<term>Chlorhydrate de venlafaxine</term>
<term>Citalopram</term>
<term>Clomipramine</term>
<term>Désipramine</term>
<term>Fluoxétine</term>
<term>Imipramine</term>
<term>Miansérine</term>
<term>Nortriptyline</term>
<term>Paroxétine</term>
<term>Sertraline</term>
<term>Triazoles</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Trouble dépressif majeur</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Bayes Theorem</term>
<term>Child</term>
<term>Confounding Factors (Epidemiology)</term>
<term>Double-Blind Method</term>
<term>Drug Administration Schedule</term>
<term>Evidence-Based Medicine</term>
<term>Humans</term>
<term>Randomized Controlled Trials as Topic</term>
<term>Research Design</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Calendrier d'administration des médicaments</term>
<term>Enfant</term>
<term>Essais contrôlés randomisés comme sujet</term>
<term>Facteurs de confusion (épidémiologie)</term>
<term>Humains</term>
<term>Médecine factuelle</term>
<term>Méthode en double aveugle</term>
<term>Plan de recherche</term>
<term>Résultat thérapeutique</term>
<term>Théorème de Bayes</term>
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<front><div type="abstract" xml:lang="en">Major depressive disorder is one of the most common mental disorders in children and adolescents. However, whether to use pharmacological interventions in this population and which drug should be preferred are still matters of controversy. Consequently, we aimed to compare and rank antidepressants and placebo for major depressive disorder in young people.</div>
</front>
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<li>Australie</li>
<li>Canada</li>
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<li>Melbourne</li>
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<orgName><li>Université Pierre-et-Marie-Curie</li>
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<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Cipriani, Andrea" sort="Cipriani, Andrea" uniqKey="Cipriani A" first="Andrea" last="Cipriani">Andrea Cipriani</name>
</region>
</country>
<country name="République populaire de Chine"><noRegion><name sortKey="Zhou, Xinyu" sort="Zhou, Xinyu" uniqKey="Zhou X" first="Xinyu" last="Zhou">Xinyu Zhou</name>
</noRegion>
<name sortKey="Liu, Lanxiang" sort="Liu, Lanxiang" uniqKey="Liu L" first="Lanxiang" last="Liu">Lanxiang Liu</name>
<name sortKey="Liu, Yiyun" sort="Liu, Yiyun" uniqKey="Liu Y" first="Yiyun" last="Liu">Yiyun Liu</name>
<name sortKey="Pu, Juncai" sort="Pu, Juncai" uniqKey="Pu J" first="Juncai" last="Pu">Juncai Pu</name>
<name sortKey="Qin, Bin" sort="Qin, Bin" uniqKey="Qin B" first="Bin" last="Qin">Bin Qin</name>
<name sortKey="Yang, Lining" sort="Yang, Lining" uniqKey="Yang L" first="Lining" last="Yang">Lining Yang</name>
<name sortKey="Zhang, Yuqing" sort="Zhang, Yuqing" uniqKey="Zhang Y" first="Yuqing" last="Zhang">Yuqing Zhang</name>
</country>
<country name="Italie"><noRegion><name sortKey="Del Giovane, Cinzia" sort="Del Giovane, Cinzia" uniqKey="Del Giovane C" first="Cinzia" last="Del Giovane">Cinzia Del Giovane</name>
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<country name="Australie"><region name="Victoria (État)"><name sortKey="Hetrick, Sarah E" sort="Hetrick, Sarah E" uniqKey="Hetrick S" first="Sarah E" last="Hetrick">Sarah E. Hetrick</name>
</region>
<name sortKey="Coghill, David" sort="Coghill, David" uniqKey="Coghill D" first="David" last="Coghill">David Coghill</name>
<name sortKey="Hazell, Philip" sort="Hazell, Philip" uniqKey="Hazell P" first="Philip" last="Hazell">Philip Hazell</name>
<name sortKey="Xie, Peng" sort="Xie, Peng" uniqKey="Xie P" first="Peng" last="Xie">Peng Xie</name>
</country>
<country name="États-Unis"><region name="Californie"><name sortKey="Whittington, Craig" sort="Whittington, Craig" uniqKey="Whittington C" first="Craig" last="Whittington">Craig Whittington</name>
</region>
<name sortKey="Michael, Kurt D" sort="Michael, Kurt D" uniqKey="Michael K" first="Kurt D" last="Michael">Kurt D. Michael</name>
</country>
<country name="Allemagne"><region name="Bavière"><name sortKey="Leucht, Stefan" sort="Leucht, Stefan" uniqKey="Leucht S" first="Stefan" last="Leucht">Stefan Leucht</name>
</region>
</country>
<country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Cuijpers, Pim" sort="Cuijpers, Pim" uniqKey="Cuijpers P" first="Pim" last="Cuijpers">Pim Cuijpers</name>
</region>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Cohen, David" sort="Cohen, David" uniqKey="Cohen D" first="David" last="Cohen">David Cohen</name>
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<country name="Canada"><region name="Ontario"><name sortKey="Ravindran, Arun V" sort="Ravindran, Arun V" uniqKey="Ravindran A" first="Arun V" last="Ravindran">Arun V. Ravindran</name>
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Serveur d'exploration sur les relations entre la France et l'Australie

Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.

Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.

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